This study was performed to compare endodontic regeneration outcome in necrotic mature single rooted teeth with periapical radiolucency using platelet rich fibrin (PRF) \& concentrated growth factor (CGF) as a different natural scaffold by evaluation of: * Regaining pulp sensibility by thermal test (hot and cold) * Periapical healing using digital radiography and selected samples will be evaluated using Cone Beam Computed Tomography (CBCT).
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healing
Timeframe: 1 year