UnknownPhase 2

Combined Procedures in the Treatment of Severe Acne Scars

48 participantsStarted 2024-03-01

Plain-language summary

Many methods utilize for acne scar treatment including laser, cosmetic filler, microneedling, local tumescent, Subcision and chemical peels. These procedures can be used individually or as a combination therapy. Combining procedures give better results. In our study we will try in the period from March 2024 to March 2026, to assess the efficacy of combination of scar subcision with platelet rich plasma, Polydioxanone mono threads or fractional Carbon dioxide laser in the treatment of severe atrophic acne scars with 1:1:1 ratios and to compare between these modalities regarding safety and efficacy.

Who can participate

Age range18 Years – 40 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: • Patients with severe atrophic acne scars (as per Goodman and Baron's acne qualitative scar grading scale) Exclusion Criteria: * Patients with active acne lesions. * Patients having a keloid formation tendency. * Patients with a history of bleeding disorder or severe anemia. * Pregnant or lactating women. * Patients received any treatment for scars in the last 6 months. * Patients using drugs causing photosensitivity or systemic retinoids in the previous 6 months (for laser group).

What they're measuring

Management of severe atrophic acne scars

Timeframe: 2 years

Trial details

NCT IDNCT06227481

SponsorAl-Azhar University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-03-01

Contact for this trial

Ahmed O Hassan

1155162310 alproff2@gmail.com

View on ClinicalTrials.gov More Atrophic Acne Scar trials