CompletedNot Applicable

Effect of Periodontal Treatment on Adipokine Levels

Finland, Turkey (Türkiye)80 participantsStarted 2015-02

Plain-language summary

The present study aimed to determine the effect of non-surgical periodontal treatment (NSPT) on serum and salivary adipokine and interleukin-1β levels in periodontitis patients with or without type 2 Diabetes Mellitus (T2DM).

Who can participate

Age range20 Years – 60 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Diabetes mellitus should be diagnosed for ≥1 year and HbA1c level should be at least %6,5 * Periodontitis should be diagnosed for at least 4 teeth with probing depth ≥5 mm with bleeding on probing (BOP) and also radiographic alveolar bone loss should be presence * Presence of at least 15 teeth Exclusion Criteria: * Received antibiotic treatment in the previous 3 months * Smokers * Pregnancy and lactation * Received periodontal treatment in the previous 6 months * Presence of less than 15 teeth * Having major diabetic complications

What they're measuring

Serum and Salivary Resistin Levels (pg/ml)

Timeframe: Change between baseline, 1 and 3 months after non-surgical periodontal treatment

Serum and Salivary Leptin Levels (pg/ml)

Timeframe: Change baseline, 1 and 3 months after non-surgical periodontal treatment

Serum and Salivary Visfatin Levels (pg/ml)

Timeframe: Change baseline, 1 and 3 months after non-surgical periodontal treatment

Serum and saliva IL-1β levels (pg/ml)

Timeframe: Change baseline, 1 and 3 months after non-surgical periodontal treatment

Trial details

NCT IDNCT06225154

SponsorMarmara University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2016-05

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