Exercise Training and Kidney Transplantation (NCT06216015) | Clinical Trial Compass
CompletedNot Applicable
Exercise Training and Kidney Transplantation
345 participantsStarted 2015-09-30
Plain-language summary
The goal of this clinical trial is to investigate the physiological and molecular effects of exercise training in transplant recipients. The main questions it aims to answer are:
1. Can exercise training improve physical fitness and muscle strength in transplant recipients?
2. Can exercise training modulate inflammatory profile, hormones, lipid profile, and exercise-induced molecules in transplant recipients?
3. Can exercise training improve blood pressure and endothelial health in transplant patients?
Participants will be invited to an exercise training program 6-month after their transplant surgery. Body composition, physical assessment, and blood draw will be assessed at baseline and 24-weeks after exercise or control regimen.
Researchers will compare exercise group vs. routine care group to see if exercise training impact the health-related outcomes of this population.
Who can participate
Age range
18 Years – 60 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Medical Authorization:
* Stable Health Status
* Medication Consistency
* No History of Severe Cardiovascular Events
* No Major Orthopedic Issues
* Non-Smokers or Consistent Smoking Habits
* Ability to Comply with Study Protocols
Exclusion Criteria:
* Inability to Comply
* Cognitive disorders
* Unwillingness to Continue
* Unstable Health Conditions
* Physical limitations during the protocol
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Since this trial has already completed, would my doctor be able to share or access any findings about whether exercise training actually improved physical fitness or muscle strength in kidney transplant recipients like me?
2Given that muscle weakness is one of the conditions this trial focused on, how relevant is an exercise training program to my own recovery after a kidney transplant, and is something similar available to me now outside of a trial?
3This trial measured VO2peak, which reflects cardiorespiratory fitness — how concerned should my doctor be about my current fitness level after transplant, and what does that mean for my long-term kidney health?
4Since inflammation was one of the conditions being studied alongside transplant rejection, would my doctor expect exercise training to have any impact on my immune response or rejection risk after a kidney transplant?
5Because this trial is listed as Phase NA — meaning it wasn't testing a new drug or device — does that change how confident my doctor would be in recommending an exercise program as part of my standard post-transplant care?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Physical fitness - VO2peak
Timeframe: Baseline, after 24-weeks and at the end of the protocol
2
Isometric muscle strength
Timeframe: Baseline, after 24-weeks and at the end of the protocol