CompletedNot Applicable

A Prospective Evaluation of Colorado's New Statutory PDMP Mandates: Compliance and Patient Outcomes

United States89,871 participantsStarted 2025-01-09

Plain-language summary

The goal of this study is to test the impact of a clinical decision support (CDS) tool to improve health care provider practices in line with state law requiring review of the Colorado prescription drug monitoring program (PDMP) before prescribing an opioid analgesic (pain medications often called narcotics) or benzodiazepine (sedatives or muscle relaxants). The PDMP is a statewide database of filled controlled medication, allowing health care providers to review medications ordered by other health care providers in the state and identify high-risk factors for overdose. The CDS tool only appears when a relevant prescription is being written by a health care provider and is purely informational, not dictating care or changes in treatment. The study will track how the tool is used by health care providers, if an opioid or benzodiazepine prescription is signed, and future opioid use by patients.

Who can participate

Age range12 Years – 89 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

✓. Patients seen in the UCHealth Emergency Department, outpatient clinic/office or inpatient setting during the intervention period
✓. Provider initiates a prescription for an opioid or benzodiazepine
✓. patient is between 12-89 years of age, inclusive

Exclusion criteria

✕. Providers primarily practicing in dentistry, veterinary medicine, oncology, pediatrics, palliative, or hospice practices.
✕. Providers in ambulatory practices (primary care and specialty clinics) which write a total of less than 52 opioids and benzodiazepine prescriptions in the year prior to study initiation.
✕. Encounters in dentistry, veterinary medicine, oncology practices, pediatrics practices, palliative care or hospice practices
✕. Prisoners or wards of the state
✕. Age \<12 or \>89 YOA
✕. Active diagnosis of sickle cell, cancer, or in hospice care.

What they're measuring

Number of PDMP check encounters

Timeframe: 18 months

Initiated controlled medication prescription

Timeframe: 18 months

Trial details

NCT IDNCT06215560

SponsorUniversity of Colorado, Denver

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2025-07-30

View on ClinicalTrials.gov More Medication Abuse trials