Active — Not RecruitingNot Applicable

Is the Degree of Perceived Effort During Resistance Exercise Important for Improvements in Blood Glucose

United States15 participantsStarted 2024-06-12

Plain-language summary

The goal of this clinical trial is to compare the degree of effort during a resistance exercise session on blood glucose levels in individuals with prediabetes or type 2 diabetes mellitus. The main questions it aims to answer are: * Do individuals with prediabetes or type 2 diabetes mellitus need to perform resistance exercise with a high degree of effort for their blood glucose to improve? * How do they feel (their enjoyment, discomfort) after the sessions with different degrees of effort? Participants will perform 3 situations separated by at least 4 days, after being familiarized with all exercises and procedures: * One control day, when they will not exercise; * A high-effort resistance exercise session; * A low-effort resistance exercise session Researchers will measure blood glucose levels and psychological responses after these situations to see if the effort was important for the improvement of their blood glucose and how effort affected the way they felt after each situation.

Who can participate

Age range

18 Years – 75 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * age between 18 and 75 years; * presence of prediabetes (fasting glycemia between 100 and 125 mg/dL or glycated hemoglobin \[A1c\] between 5.7 and 6.4%) or T2DM (fasting glycemia 126 mg/dL or above or A1c 6.5% or above). Exclusion Criteria: * renal failure, * liver disease, * uncontrolled hypertension (equal or greater than 160 mmHg systolic and/or equal or greater than 100 mmHg diastolic), * history of severe cardiovascular problems, * in case of oral hypoglycemic drugs usage, being on them for less than 6 months, * inability to perform resistance exercise, * being pregnant or trying to become pregnant during the course of the study, * use of oral contraceptives, * prisoners, * persons requiring a legally authorized representative, * non-English speakers.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Glucose concentration

Timeframe: For 48 hours during each situation (arm) of the study

Glucose concentration

Timeframe: For 6 hours during the morning (6 am - 12 pm) of each situation (arm) of the study

Glucose concentration

Timeframe: For 6 hours during the afternoon (12 pm - 6 pm) of each situation (arm) of the study

Glucose concentration

Timeframe: For 6 hours during the evening (6 pm - 12 am) of each situation (arm) of the study

Glucose concentration

Timeframe: For 6 hours during the nocturnal period (12 am - 6 am) of each situation (arm) of the study

Time in range

Timeframe: For 48 hours during each situation (arm) of the study

Time in range

Timeframe: For 6 hours during the morning (6 am - 12 pm) of each situation (arm) of the study

Trial details

NCT IDNCT06208189

SponsorUniversity of New Mexico

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-07-30

View on ClinicalTrials.gov More PreDiabetes trials

Plain-language summary

Who can participate

Age range

18 Years – 75 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

Glucose concentration

Timeframe: For 48 hours during each situation (arm) of the study

Glucose concentration

Timeframe: For 6 hours during the morning (6 am - 12 pm) of each situation (arm) of the study

Glucose concentration

Timeframe: For 6 hours during the afternoon (12 pm - 6 pm) of each situation (arm) of the study

Glucose concentration

Timeframe: For 6 hours during the evening (6 pm - 12 am) of each situation (arm) of the study

Glucose concentration

Timeframe: For 6 hours during the nocturnal period (12 am - 6 am) of each situation (arm) of the study

Time in range

Timeframe: For 48 hours during each situation (arm) of the study

Time in range

Timeframe: For 6 hours during the morning (6 am - 12 pm) of each situation (arm) of the study