Since 1980, the global prevalence of obesity, commonly defined as a body mass index (BMI) of 30 or higher, has doubled. Importantly, high levels of central adiposity (i.e., abdominal fat) is associated with numerous PNI-related sequelae, including increased levels of psychological distress, cognitive deficits, ANS dysfunction, and immune marker abnormalities. To our knowledge, rigorous investigation of chiropractic's impact on psychoneuroimmunological (PNI)-related outcomes in people with high central adiposity is lacking. Based on limited evidence to date, it is plausible that clinically important PNI-related dysfunctions (e.g., heightened stress levels, executive function impairments, dysautonomia, immune dysregulation) common in this population could be ameliorated via chiropractic care.
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Proportion of Potential Participants Who Are Eligible.
Timeframe: From lab arrival to completion of on-site screening (up to 15 minutes)
Proportion of Participants Complying With Pre-baseline Lifestyle Restrictions
Timeframe: From start of lifestyle restriction window to lab arrival (up to 24 hours)
Proportion of Participants Able to Tolerate the Assessments
Timeframe: From enrollment to completion of baseline assessments (up to 2 hours)
Proportion of Participants Adhering to Their Prescribed Care Plan
Timeframe: From enrollment to end of treatment (up to 6 weeks)
Proportion of Participants Retained in the Study
Timeframe: From enrollment to end of treatment (up to 6 weeks)