The Anesthesia Effects of Dexmedetomidine Combined With Desflurane or Propofol in Lobectomy (NCT06207344) | Clinical Trial Compass
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The Anesthesia Effects of Dexmedetomidine Combined With Desflurane or Propofol in Lobectomy
China120 participantsStarted 2023-10-21
Plain-language summary
In one-lung ventilation surgery, compared with dexmedetomidine combined with propofol, dexmedetomidine combined with desflurane may be beneficial to accelerate patients' recovery and reduce postoperative pulmonary complications and does not increase the incidences of delirium and postoperative nausea and vomiting.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
. General anesthesia is required and the expected duration of one-lung ventilation is ≥ 1h.
. American Association of Anesthesiologists (ASA) physical condition classification I-III.
. Patients over 18 years old.
. Voluntary participation and ability to understand and sign the informed consent.
Exclusion criteria
. Obese patients (BMI\>28 kg/m2).
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Time to open eyes after anesthetics withdrawal
Timeframe: From time of anesthetic withdrawal to the first time of the patient open his or her eyes, assessed up to 2 hour.
Trial details
NCT IDNCT06207344
SponsorThe Second Affiliated Hospital of Chongqing Medical University
. Acute coronary syndrome, sinus bradycardia (heart rate \< 45 beats/min), II or III degree atrioventricular block, NYHA heart function classification III or IV.
. Patients with severe history of chronic obstructive pulmonary disease (GOLD grade III or IV of pulmonary function of chronic obstructive pulmonary disease), severe or uncontrolled bronchial asthma, pulmonary infection, bronchiectasis and thoracic deformity.
. Pulmonary artery pressure ≥60 mmHg.
. Patients with Child grade B or C of liver function.
. Patients with chronic kidney disease in stage 4 or 5.
. Patients with hyperthyroidism and pheochromocytoma.