Hemp Fiber Ingestion and Gut Permeability After Exercise

Inclusion Criteria: * Male or female cyclists, ages 18-65 years, and capable of cycling 2.25 h in the laboratory at 60% watts maximum (close to long-distance race pace). * Non-smoker, and generally healthy and without gastrointestinal diseases (irritable bowel syndrome, chronic nausea, vomiting, and diarrhea, Crohn's disease, Celiac disease, diverticulosis) or chronic diseases including cardiovascular disease (e.g., heart disease, stroke), cancer, type 1 and 2 diabetes, rheumatoid arthritis. Categorized as "low risk" using the American College of Sports Medicine screening questionnaire. * Agree to train normally, maintain weight, and avoid the regular use of large-dose vitamin and mineral supplements, herbs, and medications that influence inflammation (especially non-steroidal antiinflammatory drugs or NSAIDs) for the duration of the 10-week study and at least a 2-week period prior to the study. * Agree to taper your exercise routine prior to each of the 3 lab cycling sessions (as if preparing for a race event). * Agree to restrict (i.e., avoid high amounts of) black pepper, red pepper, garlic, curry, and other strong spices during the 3-day period prior to each lab visit. Exclusion Criteria: * Inability to comply with study requirements. * Females trying to become pregnant, or currently pregnant or breastfeeding. * Nonpregnant adults who weigh less than 110 pounds. * Any other concurrent condition which, in the opinion of the principal investigator (PI), would preclude pa…