Cannabinoids for Pain Management and Neuroprotection From Concussion

Inclusion Criteria: * Healthy male adults between 18-35 years of age that compete in contact sport athletics * No known cerebrovascular or cardiovascular complications * Not habitual recreational users of cannabis (i.e., \<1 day/week) or tobacco users * Agree not to consume any other cannabis or tobacco products while enrolled in the study * Agree to list any prescription medications being taken * Ability to maintain commitment to all proposed biopsychological and health questionnaires, and neuro-physiological, physiological, perceptual-cognitive, and functional motor skills laboratory tests Exclusion Criteria: * Female * Requirement to travel to the USA during study period; USA laws do not permit cross border with cannabis products * Use of cannabis-based therapy within 2 months (participants who have previously used a cannabis based therapy may be included if they have a 2 month period without use of cannabis based therapy prior to enrolment in the study) * Any level of cannabis in blood samples when sampled at the commencement of the study * Medically supervised for anxiety, depression, or other neurological conditions * Initiation or dosage change of oral or injected steroids within past 3 months * Allergy or known intolerance to any of the compounds within the study preparation * Inability to attend assessments on a regular basis at the pre-determined times, or failure to take drug on a daily basis * Clinically significant cardiac, renal or hepatic disease (as assesse…