Multimodal Profiling of Response to Pediatric Comprehensive Behavioral Intervention for Tics

Inclusion Criteria: * Age 10-17 years at time of enrollment. * Current chronic motor and/or vocal tics, defined as tics for at least 1 year without a tic-free period of more than 3 consecutive months. Tics must not be due to a medical condition or the direct physiological effects of a substance. * At least moderate tic severity, defined as a Yale Global Tic Severity Scale total score ≥14 (≥9 for those with motor or vocal tics only). * Full scale IQ greater than 70. * Child participant required to have English fluency to ensure comprehension of study measures and instructions. * To increase external validity of findings, we will include participants taking psychotropic medications that have been stable for 4 weeks and expect to remain stable for the study period. Individuals receiving non-tic related psychotherapy involving procedures that overlap with CBIT can be eligible to participate if they refrain from receiving treatment once enrolled through the post-treatment assessment. All concurrent treatments will be monitored. Exclusion Criteria: * Inability to undergo MRI (e.g., metal in body, claustrophobia, orthodontia) and/or EEG. * Active suicidality Previous diagnosis of psychosis, cognitive disability, or structural brain disease that in the investigator opinion would impede participation. * History of seizure disorder * Active substance abuse or dependence. * Presence of another psychiatric or medical condition requiring immediate treatment and/or for which delay of tr…