UnknownNot Applicable

Nutritional Study to Determine the Effect of Fish Oil on Atopic Dermatitis

Norway60 participantsStarted 2023-12-01

Plain-language summary

Atopic Dermatitis is associated with pronounced changes in the lipid composition in the skin. The lipid changes are influenced by and contributing to both the inflammatory circuit and the impaired barrier as well as changes in the skin microbiome This nutritional study will investigate the effect of long-chain monounsaturated fatty acid Cetoleic acid on atoptic dermatitis. Earlier studies have shown a anti-inflammatory effect of celoteic acid.

Who can participate

Age range

18 Years – 80 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Women and men 18-80 years of age. * Diagnosed with active mild to moderate atopic dermatitis with an EASI of 1.1- 21.0. * Willing to refrain from oil supplements (omega-3, borage, evening primrose, etc.) for 1 month before study begin (washout) and during the study * Willing to take the study supplement for 6 months Exclusion Criteria: * Known allergy to fish products * Subjects known to be pregnant or breast feeding * Subjects perceiving systemically administered medication for AD (other than topical) * Subjects with auto-immune diseases (except asthma and seasonal/perennial rhinitis) * Subjects with a diagnosis of other skin diseases

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

EASI

Timeframe: 6 months

DQLI

Timeframe: 6 months

POEM

Timeframe: 6 months

Itch Numerical Rating Scale (NRS)

Timeframe: 6 months

Trial details

NCT IDNCT06194045

SponsorMøreforsking AS

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2024-10-10

Contact for this trial

Lisa Kolden Midtbø, PhD

+47 70 11 16 00 lisa.kolden.midtbo@moreforsking.no

View on ClinicalTrials.gov More Atopic Dermatitis trials

Plain-language summary

Who can participate

Age range

18 Years – 80 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.