Evaluate the Effectiveness of Progestin-Primed Versus GnRH Antagonist Protocols in Vietnamese Wom… (NCT06191809) | Clinical Trial Compass
UnknownNot Applicable
Evaluate the Effectiveness of Progestin-Primed Versus GnRH Antagonist Protocols in Vietnamese Women Undergoing In-vitro Fertilization
Vietnam200 participantsStarted 2023-02-14
Plain-language summary
This study aims to evaluate the efficacy of the progestin-primed ovary stimulation (PPOS) protocol compared to the standard GnRH antagonist (GnRH\_ant) protocol across successive stages in a controlled ovarian stimulation (COS) and ICSI procedure.
Who can participate
Age range
20 Years – 45 Years
Sex
FEMALE
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
Women meeting the sample selection criteria are as follows:
* Women age 20 to 45 years old.
* Infertility due to male factors, fallopian tube factors, or unknown causes.
* Undergoing IVF in one COS cycle and intended to apply either GnRH antagonist protocol or PPOS protocol
* Voluntary participation in research.
Exclusion Criteria:
* Any contraindications to ovarian stimulation and IVF/ICSI treatment
* Hyperprolactinemia or other endocrine diseases.
* Those who took hormone drugs within the past 3 months
* Suffering from systemic diseases such as kidney failure, lupus erythematosus, depression, etc.
* Abnormal structure of the uterine cavity.
* Patients with endometriosis or cancer
* Random-start cycles.
* Oocyte donation cycles
* Perform embryo biopsy.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
The quantity of day 3rd and day 5th embryos and MII oocytes
Timeframe: 11 months after initiation of treatment in either arm