Effects of Cycling and Virtual Reality on Thinking Speed in Persons With MS (PACE-MS) (NCT06191380) | Clinical Trial Compass
CompletedNot Applicable
Effects of Cycling and Virtual Reality on Thinking Speed in Persons With MS (PACE-MS)
United States23 participantsStarted 2024-02-12
Plain-language summary
To compare the effects of cycling exercise with different types of virtual reality on processing/thinking speed in persons with multiple sclerosis (MS).
Who can participate
Age range18 Years – 70 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Speak English as their primary language
* Confirmed MS diagnosis by a neurologist
* Be relapse and steroid-free for at least 30 days
* Mild-to-moderate self-report mobility disability
Exclusion Criteria:
* History of neurological disorders besides MS or history of uncontrolled psychiatric disorders (ex: major depression)
* Have contraindications to exercise, based on the Physical Activity Readiness Questionnaire (PAR-Q)
* Currently use medications that may impact cognition (ex: steroids, benzodiazepines)
* Currently pregnant
* Severe cognitive impairment as measured by the Modified Telephone Interview of Cognitive Status (TICS-M)
* No indication of age-related mild cognitive impairment or dementia, based on the MOCA-Blind (i.e., MOCA-Blind ≥19).
* High likelihood of motion sickness
* Regular cyclist, defined as cycling for at least 150 minutes/week
What they're measuring
1
Modified Flanker Task (MFT)
Timeframe: Immediately before the single bout of cycling and 5 minutes after the single bout of cycling.