CompletedNot Applicable

Short Term Efficacy of 5% Dextrose Injection With Ultrasound Guided Nerve Hydrodissection Method in CTS

Turkey (Türkiye)44 participantsStarted 2021-11-01

Plain-language summary

Hydrodissection injection method; It is a safe and effective injection method in peripheral nerve compression that aims to release the adhesions by separating the nerve from the surrounding connective tissues through the liquid given by injection. Perineural injection of 5% dextrose is analgesic in neuropathic pain, although the mechanism is not fully defined. USG-guided 5% dextrose injection using nerve hydrodissection method is promising in the treatment of CTS. In our study, we aimed to investigate the short-term (4 weeks) efficacy of 5% dextrose injection using USG-guided nerve hydrodissection method in combination with wrist splint treatment in patients with mild to moderate carpal tunnel syndrome (CTS) and whether this treatment can provide additional benefit to wrist splint treatment.

Who can participate

Age range

18 Years – 65 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients with clinical symptoms for at least 3 months * Patients with paresthesia or dysesthesia in the fingers * Patients diagnosed with mild or moderate carpal tunnel syndrome by EMG Exclusion Criteria: * Patients with severe carpal tunnel syndrome * Patients with polyneuropathy, cervical radiculopathy, brachial plexopathy and thoracic outlet syndrome * Patients with a history of wrist surgery * Patients within 6 months of steroid injection for carpal tunnel syndrome * Patients with infection at the treatment site * Patients with coagulation disorders or on coumadin * Pregnant patients * Patients with a history of malignancy, rheumatologic disease * Patients with any other painful pathology in the upper extremity

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Visual Analogue Scale (VAS)

Timeframe: Start of the study (week 0) and at the end of the 4th week.

Boston Carpal Tunnel Questionnaire (BCTQ)

Timeframe: Start of the study (week 0) and at the end of the 4th week.

Trial details

NCT IDNCT06189651

SponsorIstanbul Physical Medicine Rehabilitation Training and Research Hospital

Sponsor typeOTHER_GOV

Study typeINTERVENTIONAL

Primary completion2022-11-01

View on ClinicalTrials.gov More Carpal Tunnel Syndrome trials