RecruitingNot Applicable

Hypertension Explored in Long-term Postpartum Follow-up in Later Life

United Kingdom200 participantsStarted 2023-03-23

Plain-language summary

The purpose of this study is to understand more about why women who have had hypertensive pregnancies may be at increased risk of high blood pressure and why these women are often at increased risk of heart and blood vessel disease later in life.

Who can participate

Age range

30 Years – 70 Years

Sex

FEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Inclusion Criteria * Participant is willing and able to give informed consent for participation in the study * Female who had a pregnancy 10 to 25 years prior * Able (in the investigator's opinion) and willing to comply with all study requirements. * Adequate understanding of verbal and written English Exclusion Criteria: * The participant may not enter the study if ANY of the following apply: * Over 10 weeks pregnant during the course of the study * Evidence of congenital heart disease or significant chronic disease relevant to cardiovascular or metabolic status * Any significant disease or disorder which, in the opinion of the investigator, might influence the participant's ability to participate in the study For exclusion of MRI component only: • Unsuitable for MRI based on the responses to the MRI screening form. The participant may still be included in other parts of the study.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Cardiac right ventricular mass

Timeframe: Participants will be recruited at 10 to 25 years post index pregnancy and assessed up to 40 years post index pregnancy. Index pregnancy is defined as the pregnancy which we first collected data from.

Trial details

NCT IDNCT06187012

SponsorUniversity of Oxford

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2027-11-01

Contact for this trial

Katie Suriano

01865226845 helpful@cardiov.ox.ac.uk

View on ClinicalTrials.gov More Hypertension trials