This research project aims to analyze the effects of different resistance training volumes on cognitive function, oxidative stress, immunological response, lipid profile, glycemic status, liver function, muscle function, hemodynamic response, and physical performance in individuals with mild cognitive impairment. First the investigators will analyze the effects of a single resistance training session (acute effects) with one and three sets on hemodynamic and physical performance in individuals with mild cognitive impairment. After, the investigators will analyze the effects of an 8-week resistance training program with one or three sets on cognitive function, oxidative stress, immunological response, lipid profile, glycemic status, liver function, muscle function, hemodynamic response, and physical performance in individuals with mild cognitive impairment. The investigators hypothesize that a single resistance training session of one or three sets will increase the acute hemodynamic and physical performance stress in individuals with mild cognitive impairment, although with a higher magnitude in the session with three sets. Furthermore, we hypothesize that eight weeks of resistance training with one or three sets will induce similar improvements in cognitive function, oxidative stress, immunological response, lipid profile, glycemic status, liver function, muscle function, hemodynamic response, and physical performance in individuals with mild cognitive impairment.
Age range
50 Years
Sex
ALL
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Systolic blood pressure (SBP)
Timeframe: Change from baseline to 0 minutes and 72 hours after the sessions
Handgrip strength (HGS)
Timeframe: Change from baseline to 0 minutes and 72 hours after the sessions
Dementia Rating Scale-2 (DRS-2)
Timeframe: Change from baseline to week 8
Brain-Derived Neurotrophic Factor (BDNF)
Timeframe: Change from baseline to week 8
Short Physical Performance Battery (SPPB)
Timeframe: Change from baseline until week 8