CompletedNot Applicable

Correlation Between Angle Closure Glaucoma Data and Lens Zonule Status

China263 participantsStarted 2020-12-01

Plain-language summary

The goal of this observational study is to discuss the correlation between primary angle-closure glaucoma and the state of the suspended ligament of the lens and the pathogenesis of PACG by measuring the biological data of primary angle-closure glaucoma and observing its anatomical changes.

Who can participate

Age range

47 Years – 91 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * The depth of the anterior chamber is normal, and the whole corner of the chamber is open; * The cup-to-plate ratio is less than 0.5; * No family history of glaucoma. Exclusion Criteria: * Previous history of trauma or internal eye surgery in both eyes or one eye; * Used "pilocarpine", "atropine" and other drugs to change the size of the pupil and the shape of the chamber Angle within 1 week; * Combined with other eye diseases affecting the Angle and suspension ligament, such as uveitis, ciliary cyst, high myopia, retinal diseases, etc.; * Can not cooperate with UBM and Angle scopy; * Refuse to participate in this researcher.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Axial Length (AL), Lens Thickness (LT),Lens Vault (LV), Pupil Diameter (PD),

Timeframe: before operation

Anterior Chamber Depth (ACD) in seat and rectum position, White To White (WTW), pupil vault (LV), pupil diameter (PD), The Lens Zonular Length (LZL) and Angle Opening Distance at 500μm (AOD500) in the upper, lower, nasal and temporal directions

Timeframe: before operation

Trial details

NCT IDNCT06184620

SponsorGuangfu Dang

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2023-03-30

View on ClinicalTrials.gov More Primary Angle Closure Glaucoma trials

Who can participate

Age range

47 Years – 91 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

Axial Length (AL), Lens Thickness (LT),Lens Vault (LV), Pupil Diameter (PD),

Timeframe: before operation