By InvitationNot Applicable

Optimizing Care for Challenging People Living With HIV

Taiwan210 participantsStarted 2024-03-18

Plain-language summary

Conduct an intervention combining social and behavioral health models with digital health technologies to improve their adherence to their medication schedules. The success of the intervention is assessed by comparing adherence rates before and after its implementation to see if there's a notable enhancement in how well patients follow their antiretroviral therapy.

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Exclusion criteria

. Under 18 years of age.
. Illiterate.
. Non-consenting individuals.
. Less than 365 days from the initial use of antiretroviral drugs to the assessment for inclusion in the study.
. Inability to obtain complete medication records for the 365 days prior to inclusion.
. Lack of a smart phone.
. No willingness to return for follow-up at the participating hospital.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Change in HIV Viral Load from Baseline to 1st and 2nd Follow-Up

Timeframe: At baseline, 84th (+-14) day after enrollment, and 168th (+-14) day after enrollment

Change in CD4 Count from Baseline to 1st and 2nd Follow-Up

Timeframe: At baseline, 84th (+-14) day after enrollment, and 168th (+-14) day after enrollment

Change in Quality of Life Score (WHOQOL-BREF Taiwan Version) from Baseline to 1st and 2nd Follow-Up

Timeframe: At baseline, 84th (+-14) day after enrollment, and 168th (+-14) day after enrollment

Change in HIV symptoms index (HIV-SI) in score from Baseline to 1st and 2nd Follow-Up

Timeframe: At baseline, 84th (+-14) day after enrollment, and 168th (+-14) day after enrollment

Change in Self-Reported Antiretroviral Therapy (ART) Medication Adherence from Baseline to 1st and 2nd Follow-Up

Timeframe: At baseline, 84th (+-14) day after enrollment, and 168th (+-14) day after enrollment

Trial details

NCT IDNCT06183723

SponsorKaohsiung Medical University Chung-Ho Memorial Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-12-31

View on ClinicalTrials.gov More Adherence, Medication trials

Plain-language summary

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Exclusion criteria

. Under 18 years of age.
. Illiterate.
. Non-consenting individuals.
. Less than 365 days from the initial use of antiretroviral drugs to the assessment for inclusion in the study.
. Inability to obtain complete medication records for the 365 days prior to inclusion.
. Lack of a smart phone.
. No willingness to return for follow-up at the participating hospital.

What they're measuring

Change in HIV Viral Load from Baseline to 1st and 2nd Follow-Up

Timeframe: At baseline, 84th (+-14) day after enrollment, and 168th (+-14) day after enrollment

Change in CD4 Count from Baseline to 1st and 2nd Follow-Up

Timeframe: At baseline, 84th (+-14) day after enrollment, and 168th (+-14) day after enrollment

Change in Quality of Life Score (WHOQOL-BREF Taiwan Version) from Baseline to 1st and 2nd Follow-Up

Timeframe: At baseline, 84th (+-14) day after enrollment, and 168th (+-14) day after enrollment

Change in HIV symptoms index (HIV-SI) in score from Baseline to 1st and 2nd Follow-Up

Timeframe: At baseline, 84th (+-14) day after enrollment, and 168th (+-14) day after enrollment

Change in Self-Reported Antiretroviral Therapy (ART) Medication Adherence from Baseline to 1st and 2nd Follow-Up

Timeframe: At baseline, 84th (+-14) day after enrollment, and 168th (+-14) day after enrollment