One of the most undesired side effects of fixed orthodontic treatment is white spot lesions (WSLs), that appear on the buccal surface of teeth and cause aesthetic problems. The aim of this prospective study was to quantitively evaluate the remineralization effect of casein phosphopeptide-amorphous calcium fluorophosphate (CPP-ACFP) containing (MI Paste Plus®) and hydroxyapatite, xylitol and fluoride containing (Remin Pro®) agents in remineralizing post orthodontics white spots using Quantitive Light-Induced Fluorescence Method (QLF) and ICDAS II criteria, compared to a control group in whom just a routine home care was instructed. Thirty-nine individuals who had recently completed orthodontic treatment, had at least one WSL on upper anterior teeth and aged between 12-25 years were included. The participants were randomly assigned into three groups of 13 each; (1) MI Paste Plus + routine home care; (2) Remin Pro + routine home care; and (3) routine home care (control). The treatment/ observation period was 12 weeks after bracket debonding. Fluorescence loss (∆F, %), lesion area (LA, mm2), lesion volume (∆Q, % × mm2), maximum fluorescence loss (∆Fmax), ICDAS II criteria of WSLs were measured at beginning (T0) and 4 (T1), 8 (T2), and 12 (T3) weeks later. Statistical significance was set at p\<0.05.
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Mineral Content Assessment (ΔF / Depth of lesion)
Timeframe: The patients were evaluated at baseline (T0) and every 30 days intervals for 3 months.
Mineral Content Assessment (LA / Lesion area)
Timeframe: The patients were evaluated at baseline (T0) and every 30 days intervals for 3 months.
Mineral Content Assessment (∆Q / Lesion volume)
Timeframe: The patients were evaluated at baseline (T0) and every 30 days intervals for 3 months.
Mineral Content Assessment (∆Fmax / Maximum fluorescence loss)
Timeframe: The patients were evaluated at baseline (T0) and every 30 days intervals for 3 months.