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Preoperative Administration of Lugols Solution in Toxic Thyroid Diseases (TD): A Prospective Study

Greece50 participantsStarted 2023-12-15

Plain-language summary

Lugol's solution and other preparations containing iodide have been used as an adjuvant treatment in patients with toxic disease planned for thyroidectomy. However, no conclusive evidence supporting the benefits of preoperative treatment with LS for patients with toxic goiters. This trial aims to provide new insights into future recommendations.

Who can participate

Age range18 Years – 80 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients ≥18 years of age * Toxic thyroid disease, treated with antithyroid drugs, euthyroid and proposed for total thyroidectomy * Written informed consent Exclusion Criteria: * prior thyroid or parathyroid surgery, * hyperparathyroidism that requires associated parathyroidectomy, * thyroid cancer that requires adding a lymph node dissection, * iodine allergy, * consumption of lithium or amiodarone, * medically unfit patients (ASA-IV), * breastfeeding women, * preoperative vocal cord palsy and * planned endoscopic, video-assisted or remote access surgery.

What they're measuring

Thyroidectomy complications rate

Timeframe: 24 hours postoperatively

Trial details

NCT IDNCT06176976

SponsorAristotle University Of Thessaloniki

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-01

View on ClinicalTrials.gov More Toxic; Thyroid trials