Use of Cinnamomum Verum for Induction of Labor. Double Blind Randomized Clinical Trial (NCT06164613) | Clinical Trial Compass
RecruitingPhase 2
Use of Cinnamomum Verum for Induction of Labor. Double Blind Randomized Clinical Trial
Honduras70 participantsStarted 2023-12-04
Plain-language summary
The purpose of the research protocol is to evaluate the effectiveness of Cinnamomum verum extract for the initiation of labor. Cinnamaldehyde ((E)-3-Phenylprop-2-enal) is an α, β unsaturated aromatic aldehyde, derived from cinnamon (Cinnamomum Verum oil) used as a flavoring; It is a clear yellowish liquid substance, with a strong odor and flavor. It is the main component of cinnamon (63%), giving it its physicochemical properties. Cinnamon has been an element of empirical use for the beginning of labor, however, its effectiveness has not been demonstrated.
Cinnamon has been reported for its ethnopharmacological properties in pregnancy, being used to facilitate childbirth, as a lactagogue and for postpartum recovery. In Honduras, its use has been reported to relieve nausea and vomiting during pregnancy, to reduce abdominal pain. , reduction of lower limb edema, to relieve anxiety during labor, as well as a lactagogue without convergent opinions.
Who can participate
Age range14 Years – 45 Years
SexFEMALE
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Inclusion criteria
✓. Delivery of an informed consent form signed and dated by parents or guardian and patient
✓. Declared willingness to comply with all study procedures and availability for the duration of the study.
✓. provision of appropriate consent and assent
✓. Willingness and ability to participate in study procedures
✓. Patients under 18 years of age
✓. Full-term pregnancies (37-41 Weeks of Gestation).
✓. Nulliparity
✓. Have your own cell phone
Exclusion criteria
✕. Current use of antihypertensive or hypoglycemic medications
✕. Presence of non-curable chronic diseases prior to pregnancy or during pregnancy such as hypertension, diabetes, hypothyroidism
✕. Infections (urinary tract infection, chorioamnionitis) present at the time of the study (diagnosed with symptoms or leukocytes \>12,500 or pathological urine examination)
✕. Allergies to cinnamaldehyde or cinnamon, canola oil