RecruitingNot Applicable

Chronic Endometritis and Benefits of Antibiotics in Women With Recurrent Miscarriage

Hong Kong175 participantsStarted 2024-04-01

Plain-language summary

The aim of the study is to estimate the incidence of CE, evaluate the endometrial microorganism of CE, and investigate the therapeutic benefits of antibiotics for women with unexplained recurrent miscarriage and CE.

Who can participate

Age range

20 Years – 45 Years

Sex

FEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Women with a history of 2 or more consecutive miscarriages before 24 weeks of gestation * Women aged 20-45 years old Exclusion Criteria: * Uncorrected uterine anomalies, such as the septate or bicornuate uterus, fibroids (submucous/intramural) * Untreated hydrosalpinx * Antiphospholipid syndrome * Known clinical autoimmune disease * Undergoing immunotherapy * Abnormal thyroid function * Abnormal karyotyping of couples * Known immunodeficiency pathologies such as diabetes or HIV * Currently taking other antibiotics or other trial medications or TCM; * Currently or previously involved in other clinical trials with medication intake; * Those with active pelvic inflammatory disease or suspicion of infection etc.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

the incidence of chronic endometritis in local women with unexplained recurrent miscarriage

Timeframe: 31 January 2027

Trial details

NCT IDNCT06163092

SponsorChinese University of Hong Kong

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2026-01-31

Contact for this trial

Stacey Wong, BSc

35051764 staceywong@cuhk.edu.hk

View on ClinicalTrials.gov More Recurrent Miscarriage trials