Confirmatory Study: Assessing the Efficacy and Safety of the AcusMu Microneedle Patch in Treating Periorbital Wrinkles

Inclusion Criteria: * Participants aged 18 to 99 (regardless of race or gender). * Diagnosed with mild or moderate periorbital wrinkles by a dermatologist. Exclusion Criteria: * Participants with open wounds or active infections on their skin. * Individuals involved in other studies that could interfere with this trial. * Pregnant, breastfeeding, or planning to become pregnant during the trial. * Those with significant medical conditions such as cancer, liver disease, diabetes, kidney disease, or cardiovascular disorders. * Individuals who have undergone alternative treatments for periorbital wrinkles in the past six months (e.g., laser therapy, radiofrequency). * Participants concurrently receiving alternative treatments for periorbital wrinkles.