The goal of this crossover study is to compare urine drug concentrations using a continuous vibrating mesh nebulizer versus a breath-actuated vibrating mesh nebulizer in healthy volunteers. The main questions it aims to answer are: * Whether breath-actuation nebulizer delivers higher inhaled drug dose, resulting in higher urine drug concentrations compared to continuous nebulization. * Whether the different nebulizer modes deliver inhaled drug resulting in different effects on physiological parameters, including heart rate, respiratory rate, blood pressure, and blood oxygen saturation. Participants will * Inhale one dose (2.5mg) of salbutamol via continuous vs. breath-actuated nebulize mode. * collect urine samples at multiple timepoints before and after nebulization to quantify drug elimination. Researchers will compare the continuous and breath-actuated modes of vibrating mesh nebulizers to determine if breath-actuation improves drug delivery efficiency compared to continuous nebulization.
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Urinary salbutamol concentration
Timeframe: Urine samples will be collected at 30 minutes before nebulization, at 30 minutes, and 24 hours after nebulization.