The Physiological Study of Haemodynamic and Microcirculatory Evolution before/after Transcatheter Aortic Valve Replacement (TAVI) aims to investigate the physiological changes induced by the implantation of a prosthetic aortic valve on blood vessels in patients with severe aortic stenosis. The hypothesis of the study is that adaptive microcirculatory phenomena occur during TAVI implantation. The results of preoperative assessment of microcirculatory functional reserve differ according to whether or not organ dysfunction occurs after TAVI. There is a progressive adaptation of the microcirculation to the new cardiovascular load conditions after TAVI. Early features of this adaptation are associated with the occurrence of short- and medium-term complications.
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Modification in arterial stiffness in large- and small-caliber arteries
Timeframe: 24 hours
Modification in plasma Vascular Endothelium Growth Factor levels
Timeframe: 24 hours
Modification in skin surface temperature gradient
Timeframe: 24 hours
Modification in reactive hyperemia
Timeframe: 24 hours