Noninvasive Cortical Neurostimulation For Diabetic Neuropathic Pain

Inclusion Criteria: * Minimum age of 18 years. * Type-1 diabetes * Clinically established peripheral neuropathy * DN4 of ≥4 points indicating that the patient is suffering from neuropathic pain. * NRS pain scores \>3 * Acceptable screening blood samples according to medical judgement * Signed informed consent Exclusion Criteria: * Contraindications to MRI * Not being able to understand Danish (written and/or verbally) * Not being able to comply with the study procedures including home-treatment e.g., due to senile dementia, etc. * Previous brain surgery * Present alcohol or drug abuse * Major mental and psychiatric disorders * Pregnancy * Active cancer-disease * Known neural damage or disease in the neural system (e.g., MS or Guillain-Barre) other than diabetic neuropathy * Previous chemotherapy or intake of experimental medicine * Active herpes simplex virus or varicella zoster virus infection or known HIV * Other reasons for limb pain (e.g., critical limb ischemia and lower back pain with radiating pain etc.)