CompletedNot Applicable

A Study Assessing the Effects of an Experimental Dentifrice in Maintaining Tooth Color Following Tooth Bleaching

United States160 participantsStarted 2023-11-27

Plain-language summary

The main aim of this study is to investigate the ability of an experimental dentifrice containing 5 percent (%) potassium nitrate (KNO3), 1% alumina and 5% sodium tripolyphosphate (STP), to maintain tooth color and reduce extrinsic dental stain accumulation following peroxide tooth bleaching compared to a regular fluoride dentifrice.

Who can participate

Age range18 Years – 65 Years

SexALL

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Inclusion criteria

✓. Teeth suitable for peroxide bleaching and gradable for tooth color and suitable for MLSI evaluation with no significant defects, calculus, restorations, crowns or veneers that could impact peroxide tooth bleaching performance or study evaluations as judged by the clinical examiner.
✓. Facial surfaces of maxillary anterior 6 teeth (tooth numbers 6-11) \[Universal tooth number system\] with mean Vita Bleached guide shade greater than or equal to (\>=)13 at Visits 1 and 2.
✓. Having no lesions of the teeth or oral cavity that could interfere with the study evaluations.
✓. Having a minimum of 16 natural teeth.

What they're measuring

Adjusted Mean VITA Shade Score at 24 Weeks After Tooth Bleaching

Timeframe: At Week 24 after tooth bleaching

Trial details

NCT IDNCT06150573

SponsorHALEON

Sponsor typeINDUSTRY

Study typeINTERVENTIONAL

Primary completion2024-07-18

Results submitted2025-07-07

View on ClinicalTrials.gov More Dentin Sensitivity trials