An Investigation of the Effects of a Royal Jelly and Bee Venom-Derived Skin Cream on Skin Health … (NCT06148766) | Clinical Trial Compass
CompletedNot Applicable
An Investigation of the Effects of a Royal Jelly and Bee Venom-Derived Skin Cream on Skin Health and Signs of Aging
United States40 participantsStarted 2023-11-09
Plain-language summary
This is a virtual, single-group clinical trial that will last 8 weeks. Participants will use the Manuka Health Eternal Renewal Regenerating Face Cream with Royal Jelly and Bee Venom twice daily and complete questionnaires at Baseline, Week 2, Week 4, and Week 8.
Participants will also undergo skin analysis via the Optic Elite facial skin analysis system at Baseline and Week 8.
Who can participate
Age range
40 Years – 55 Years
Sex
FEMALE
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Female.
* 40-55 years of age.
* Must be in good general health.
* Must have concerns with overall skin health and appearance, including:
Fine lines and wrinkles The appearance of dark spots
* Must be using the same cleanser and toner for at least one month prior to starting the study.
* Must be willing to keep using the same cleanser and toner for the duration of the study.
* Must not be using oral or topical retinoids.
* In the last three months, has not introduced any new medications or supplements that target skin health.
* Must be willing to comply with the protocol.
Exclusion Criteria:
* Anyone with an allergy to bees or bee products.
* Females who are pregnant or breastfeeding.
* Unwilling to follow the protocol.
* Unwilling to maintain use of the same cleaner and toner for the duration of the study.
* Currently participating in another study.
* Use of oral or topical retinoids.
* Individuals with cystic acne or otherwise self-reported very acne-prone skin.
* Use of a prescription medication relevant to the skin.
* Anyone undergoing cosmetic procedures during the study, including Botox, laser, or chemical peel treatments.
* Anyone sensitive or allergic to any ingredients found in the products.
* Anyone with severe chronic conditions, including oncological conditions, psychiatric disorders or diabetes.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This trial used a skin cream made from royal jelly and bee venom — if I have any history of allergies to bee products, is it safe for me to even consider trying products like this?
2The trial only ran for 8 weeks and measured skin changes using a device called Optic Elite Skin Analysis — does that short timeframe and that type of measurement tell us enough about whether the cream is actually effective and safe long-term?
3Since this trial is listed as phase 'NA' and has already been completed, what do you know about the results, and how strong is the evidence compared to other established skincare treatments you might recommend?
4The trial focused on general signs of skin health and aging — given my specific skin concerns, do you think a bee venom and royal jelly-based product would be relevant to what I'm dealing with, or are there better-studied options I should try first?
5Because this study is already completed, would I be able to see the published results before deciding whether this type of product is worth discussing as part of my skincare plan?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Changes in signs of skin health over time assessed via Optic Elite Skin Analysis. [Timeframe: Baseline to Week 8]