Intervention Effect of High-Definition Transcranial Direct Current Stimulation (HD-tDCS) on Non-s… (NCT06148363) | Clinical Trial Compass
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Intervention Effect of High-Definition Transcranial Direct Current Stimulation (HD-tDCS) on Non-suicidal Self-injury (NSSI)
China40 participantsStarted 2023-09-01
Plain-language summary
To investigate the intervention effect of high-definition transcranial Direct Current Stimulation (HD-tDCS) on patients with Non-suicidal Self-injury (NSSI) and its underlying neural mechanism by magnetic resonance imaging (MRI).
Who can participate
Age range12 Years – 18 Years
SexALL
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Inclusion Criteria:
The patients were diagnosed by 2 or more senior clinical psychiatrists, meeting DSM-V criteria, and having 1 or more non-suicidal self-injurious behaviors in the last 6 months.
12-18 years of age.
The medicine has not changed in the 4 weeks prior to or after this study, and if it has to be changed, the treatment medication is required to be at a subtherapeutic dosage level.
Exclusion Criteria:
The patient has suicidal ideation or has committed suicidal behavior
T1 or T2 weighted phase magnetic resonance images show focal brain lesions
patients had neurological disorders such as epilepsy, or serious physical illnesses
patients had a history of substance abuse and drug dependence in the last 6 months or use of anticonvulsant drugs in the last 3 months
patients had received radial cranial electrical stimulation or magnetic stimulation treatment in the last 3 months or received electroconvulsive therapy in the last 6 months
patients had previous significant head trauma or EEG abnormality in the last 1 month
body-mounted devices unsuitable for treatment, such as pacemakers, artificial valves, and other metal implants.
What they're measuring
1
Changes in the number, frequency, and impulsivity of self-injurious behaviors
Timeframe: baseline and immediately after the intervention