CompletedNot Applicable

Identifying Molecular Determinants of Infertility in Men (MODIFY)

Singapore100 participantsStarted 2023-10-11

Plain-language summary

The purpose of this study is to understand the underlying mechanisms of infertility caused by unknown factors. The investigator propose to identify small non-coding RNA (sncRNA) biomarkers of infertility and advance towards developing a more accurate and robust approach for infertility diagnosis.

Who can participate

Age range21 Years – 50 Years

SexMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria * Male, aged 21 - 50 years old * Proficient in English language * Willing to comply to study protocol * Able to provide written informed consent Exclusion Criteria * Current and/or previous diagnosis of Tuberculosis, Acquired immunodeficiency syndrome (AIDs), and other sexually transmitted diseases * Experiencing severely limited mobility (eg. Wheelchair bound, need walking aid) * Diagnosed with severe unstable mental conditions (eg. Dementia, or cognitive impairment) * Alcohol or drug abuse

What they're measuring

Semen/Sperm quantity analysis

Timeframe: 1 week

Semen/Sperm quality analysis

Timeframe: 1 week

Fertility classification

Timeframe: 1 week

Sperm RNA extraction and sequencing

Timeframe: 3 months

Trial details

NCT IDNCT06147700

SponsorInstitute for Human Development and Potential (IHDP), Singapore

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2024-06-30

View on ClinicalTrials.gov More Male Infertility trials