CompletedNot Applicable

Assessment Of Peri-papillary Retinal Nerve Fiber Layer Thickness In Patients With Unilateral Branch Retinal Vein Occlusion

Egypt60 participantsStarted 2020-12-01

Plain-language summary

Several studies have indicated a relation between the development of RVO and elevated intraocular pressure (IOP) and glaucoma \[9\]. Further investigations into the structural alterations in the fellow eyes of individuals with unilateral RVO have revealed that the pRNFL is thinner than in healthy eyes, suggesting that there may be systemic risk factors for both RVO and glaucoma

Who can participate

Age range

47 Years – 68 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * patients with unilateral BRVO Exclusion Criteria: * History of retinal and/or optic nerve diseases involving glaucomatous optic disc, ischemic optic neuropathy, or optic neuritis. * History of trauma, intravitreal injections, vitreoretinal surgeries, and retinal or macular lasers. * A significant media opacity that makes it difficult to capture clear images. * No history of diabetes and/or hypertension in those recruited as the control group

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

peri-papillary retinal nerve fiber layer thickness

Timeframe: Base line

peri-papillary retinal nerve fiber layer thickness

Timeframe: 6 months post injection

peri-papillary retinal nerve fiber layer thickness

Timeframe: 12 months post injection

peri-papillary retinal nerve fiber layer thickness

Timeframe: 24 months post injection

Trial details

NCT IDNCT06146309

SponsorAl-Azhar University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2022-07-20

View on ClinicalTrials.gov More Branch Retinal Vein Occlusion trials

Plain-language summary

Who can participate

Age range

47 Years – 68 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

peri-papillary retinal nerve fiber layer thickness

Timeframe: Base line

peri-papillary retinal nerve fiber layer thickness

Timeframe: 6 months post injection

peri-papillary retinal nerve fiber layer thickness

Timeframe: 12 months post injection

peri-papillary retinal nerve fiber layer thickness

Timeframe: 24 months post injection