RecruitingNot Applicable

Clinical Application of Cytokine Adsorption Technique in AIDS Patients With Severe Pneumonia and/or Septic Shock

China60 participantsStarted 2023-10-23

Plain-language summary

Observing the Real-World Application Effectiveness of Cytokine Immune Adsorption Technology in AIDS Patients with Severe Pneumonia or septic shock.

Age range18 Years – 65 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

✓. Confirmed HIV infection;
✓. Progression to AIDS stage: CD4+ count \<200 cells/ul and/or occurrence of AIDS opportunistic infections;
✓. Age between 18 and 65 years;
✓. Meeting the diagnosis of severe pneumonia or septic shock:
✓. The criteria for severe pneumonia diagnosis refer to the 2021 ATS (American Thoracic Society) and IDSA (Infectious Diseases Society of America) guidelines for the treatment of community-acquired pneumonia;
✓. The criteria for septic shock refer to the Chinese Society of Critical Care Medicine's "Chinese Guidelines for the Emergency Treatment of Sepsis/Septic Shock (2018).

✕. Coexisting central nervous system lesions, severe liver disease, or cirrhosis;
✕. Concurrent AIDS-related or unrelated tumors;
✕. Women who are pregnant or breastfeeding;
✕. Severe underlying diseases of the heart, lungs, liver, kidneys, etc.;
✕. Alcohol abuse or drug use;
✕. The researcher believes that the overall condition of the subject affects the evaluation and completion of the trial.

Mortality rate

Timeframe: 4 weeks

NCT IDNCT06145828

SponsorGuangzhou 8th People's Hospital

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2026-10-23

Linghua Li, PhD