UnknownNot Applicable

A Comparison of Thoracic Electrical Bioimpedance and FloTrac/Vigileo

China100 participantsStarted 2023-11-20

Plain-language summary

Stroke volume variation (SVV) is an indicator used to assess the patient's volume status. The FloTrac system (Edwards Lifesciences, Irvine, CA) continuously monitors cardiac output (CO) and SVV (SVV-FloTrac) by analyzing the systemic arterial pressure wave. Numerous studies have demonstrated that SVV-FloTrac serves as a reliable indicator of fluid responsiveness. However, its peripheral invasiveness raises concerns about susceptibility to reflecting waves, damping, and vascular tone influences.In contrast, Transthoracic electrical bioimpedance (BioZ.com™) offers a non-invasive approach for continuously monitoring various hemodynamic variables. In this study, the primary aim was to assess the agreement between simultaneously measured SVV-FloTrac and SVV-BioZ.

Who can participate

Age range18 Years – 65 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Age 18≤ Age ≤65. * patients undergoinglaparoscopic elective surgery for gastrointestinal tumors under general anesthesia * 18 kg/m2≤BMI≤30 kg/m2 * ASA classification I-III * Patients signed informed consent form Exclusion Criteria: * Arrhythmias * The patient is diagnosed with severe cardiovascular disease（pulmonary arterial hypertension、left ventricular ejection fraction\< 50%、aortic aneurysm、extensive peripheral arterial occlusive disease,、significant valvulopathy） * Severe heart failure (METS\<4) * The patient is diagnosed with severe hepatic dysfunction (ChildePugh class C) * The patient is diagnosed with severe renal dysfunction (undergoing dialysis before surgery) * There is an infectious lesion on the skin or subcutaneous tissue where the non-invasive electrode piece is placed * History of allergy to anesthetic drugs * Weight\<40kg * Allergies to 6% hydroxyethyl starch, Fresenius Kabi, Deutschland

What they're measuring

The agreement between simultaneously measured SVV-FloTrac and SVV-BioZ

Timeframe: From anesthesia induction to the nonresponsive VLS about one hour.

Trial details

NCT IDNCT06143111

SponsorRenJi Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2024-12-31

Contact for this trial

Diansan Su, Dr.

+862168383702 diansansu@yahoo.com