Tracking of Red Blood Cells Using Super Resolution Ultrasound in Persons With Healthy or Overuse … (NCT06142747) | Clinical Trial Compass
RecruitingNot Applicable
Tracking of Red Blood Cells Using Super Resolution Ultrasound in Persons With Healthy or Overuse Injured Tendons
Denmark135 participantsStarted 2024-02-08
Plain-language summary
The goal of this observational study is to test whether a new ultrasound method, called SUper Resolution ultrasound imaging of Erythrocytes (SURE), can image the small blood vessels found in tendons of persons with a tendon overuse injury (tendinopathy). The main questions it aims to answer are:
* Is the method sensitive enough to detect the smallest blood vessels
* What information about the blood flow can be obtained (flow velocity, pressure, shape of the vessels)
* Can the flow in an injured tendon be distinguished from that of a healthy one
Participants will receive a non-invasive ultrasound examination of their Achilles (heel) or patellar (knee) tendon, using an advanced high frequency research ultrasound system.
Researchers will compare participants with either an Achilles or patellar tendon overuse injury to participants with healthy tendons, to see if there are distinct differences in the blood vessels that could help diagnose and treat the injuries.
Who can participate
Age range
18 Years – 70 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* 18 to 70 years of age.
* BMI below 30.
* Able to lie still for 1 minute.
* Capable of providing signed informed consent.
Exclusion Criteria:
* Pregnancy.
* Dementia.
* Smoking.
* Diabetes.
* Arthritis.
* Current or historical injuries to the tendon or surrounding tissue aside from tendinopathy.
* Medical or surgical treatments for their tendinopathy that may influence blood flow.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Vessel density (all)
Timeframe: day 0 (the study is cross-sectional)
Trial details
NCT IDNCT06142747
SponsorUniversity Hospital Bispebjerg and Frederiksberg