RecruitingPhase 2

Changes in Hemorrhage With Prophylactic Oxytocin for Dilation and Evacuation

United States150 participantsStarted 2024-05-02

Plain-language summary

The purpose of this study is to assess the effectiveness of prophylactic oxytocin on hemorrhage rates for second trimester dilation and evacuation (D\&E) in the clinic setting.

Who can participate

Age range18 Years – 55 Years

SexFEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * clinic-based D\&E at 18 weeks gestational age and above * speaks English or Spanish Exclusion Criteria: * refuses IV * history of coagulopathy * anticoagulant use in the preceding five days * chorioamnionitis or sepsis * suspected placenta accreta spectrum * intrauterine fetal demise * multiple gestation * use of misoprostol for cervical preparation

What they're measuring

Hemorrhage

Timeframe: day of procedure

Quantitative blood loss

Timeframe: day of procedure

Trial details

NCT IDNCT06141447

SponsorUniversity of Colorado, Denver

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-11-02

Contact for this trial

Megan Masten, MD

303-724-8576 megan.masten@cuanschutz.edu

View on ClinicalTrials.gov More Hemorrhage trials