CompletedNot Applicable

NGS-Based Assay of Blood Samples of Sepsis Patients for Rapid Bacterial Identification

Greece100 participantsStarted 2023-11-16

Plain-language summary

Rapid detection of microorganisms is a promising approach towards early administration of appropriate antibiotics for sepsis. This study aims to investigate the potential of a new NGS platform for the rapid diagnosis of circulating bacteria in blood.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Age equal to or above 18 years. * Both genders. * Written informed consent provided by the patient or by one first-degree relative/spouse in case of patients unable to consent. * Patients with high suspicion of infection with at least one sign of the quick SOFA score (i.e. one of mental confusion, more than 22 breaths per minute or systolic blood pressure less than 100mmHg). Exclusion Criteria: * Age below 18 years. * Denial for written informed consent. * Patients already receiving antibiotics. * Pregnancy or lactation.

What they're measuring

The rate of matching between the results of Next Generation Sequencing and the Standard-of-Care culture for patients with sepsis.

Timeframe: 7 days

Trial details

NCT IDNCT06141395

SponsorHellenic Institute for the Study of Sepsis

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2024-03-14

View on ClinicalTrials.gov More Pneumonia trials