UnknownNot Applicable

Colonization of Skin by M. Luteus Q24 Probiotic

New Zealand20 participantsStarted 2023-10-02

Plain-language summary

The purpose of this study is to evaluate the skin quality improvement and colonization efficacy following the application of probiotic Micrococcus luteus Q24 (BLIS Q24) to the face from a serum format in healthy adults.

Who can participate

Age range18 Years – 80 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

✓. In general good health 18 - 80 years of age.
✓. Practice good general body hygiene.

Exclusion criteria

✕. Have a history of autoimmune disease or are immunocompromised (have a weakened immune system).
✕. Are on concurrent antibiotic therapy or regular antibiotic use within the last 1 week.
✕. People with allergies or sensitivity to dairy.
✕. People with an open wound on the Blis Q24 application sites.

What they're measuring

Change in microbial composition following application of 1e7 cfu per dose Micrococcus luteus Q24 in serum from Day 0 (baseline) to 11 days

Timeframe: Time Frame: 11 days post intervention

Change in skin quality parameters following application of 1e7 cfu per dose Micrococcus luteus Q24 in serum from Day 0 (baseline) to 11 days

Timeframe: Time Frame: 11 days post intervention

Change in microbial composition following application of 1e6 cfu per dose Micrococcus luteus Q24 in serum from Day 0 (baseline) to 11 days

Timeframe: Time Frame: 11 days post intervention

Change in skin quality parameters following application of 1e6 cfu per dose Micrococcus luteus Q24 in serum from Day 0 (baseline) to 11 days

Timeframe: Time Frame: 11 days post intervention

Change in microbial composition following application of 1e7 cfu per dose Micrococcus luteus Q24 in serum from Day 0 (baseline) to 30 days

Timeframe: Time Frame: 30 days post intervention

Change in skin quality parameters following application of 1e7 cfu per dose Micrococcus luteus Q24 in serum from Day 0 (baseline) to 30 days

Timeframe: Time Frame: 30 days post intervention

Trial details

NCT IDNCT06137209

SponsorBLIS Technologies Limited

Sponsor typeINDUSTRY

Study typeINTERVENTIONAL

Primary completion2023-11-22

View on ClinicalTrials.gov More Microbial Colonization trials

Who can participate

Age range18 Years – 80 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

✓. In general good health 18 - 80 years of age.
✓. Practice good general body hygiene.

Exclusion criteria

✕. Have a history of autoimmune disease or are immunocompromised (have a weakened immune system).
✕. Are on concurrent antibiotic therapy or regular antibiotic use within the last 1 week.
✕. People with allergies or sensitivity to dairy.
✕. People with an open wound on the Blis Q24 application sites.

What they're measuring

Change in microbial composition following application of 1e7 cfu per dose Micrococcus luteus Q24 in serum from Day 0 (baseline) to 11 days

Timeframe: Time Frame: 11 days post intervention

Change in skin quality parameters following application of 1e7 cfu per dose Micrococcus luteus Q24 in serum from Day 0 (baseline) to 11 days

Timeframe: Time Frame: 11 days post intervention

Change in microbial composition following application of 1e6 cfu per dose Micrococcus luteus Q24 in serum from Day 0 (baseline) to 11 days

Timeframe: Time Frame: 11 days post intervention

Change in skin quality parameters following application of 1e6 cfu per dose Micrococcus luteus Q24 in serum from Day 0 (baseline) to 11 days

Timeframe: Time Frame: 11 days post intervention

Change in microbial composition following application of 1e7 cfu per dose Micrococcus luteus Q24 in serum from Day 0 (baseline) to 30 days

Timeframe: Time Frame: 30 days post intervention

Change in skin quality parameters following application of 1e7 cfu per dose Micrococcus luteus Q24 in serum from Day 0 (baseline) to 30 days

Timeframe: Time Frame: 30 days post intervention