Is There an Association Between Quadriceps Strength and Different Markers of Fragility in Patients With Cirrhosis?

Inclusion Criteria: SUBJECT : * with a diagnosis of liver cirrhosis (regardless of cirrhosis stage and etiology) * under the care of a physician practising in the University Hospital Estaing in Clermont-Ferrand * affiliated to the french social security system Exclusion Criteria: SUBJECT: * with hepatocellular carcinoma * with HIV infection * with hepatic encephalopathy grade ≥ 2 * with cognitive dysfunction * with contraindication for physical activity * with knee pain/knee disorders * pregnant or breastfeeding * under protective supervision (guardianship, curatorship, protection of the court) Inclusion Criteria for healthy volonteers: * male subjects aged 52 to 62 * female subjects aged 42 to 60 * BMI between 20 and 30 kg/m2 * no musculoskeletal problems limiting physical activity * level of physical activity \< 3 hours per week * affiliated to the french social security system Exclusion Criteria for healthy volonteers: * medical or surgical history deemed incompatible with the trial by the investigator * simultaneous participation in a trial involving a drug or medical device, or period of exclusion from such a trial * participants protected by law (under guardianship, conservatorship, or protection of the court)