Application of Perioperative Remote Ischemic Conditioning in Patients Undergoing Hepatectomy (NCT06130436) | Clinical Trial Compass
CompletedNot Applicable
Application of Perioperative Remote Ischemic Conditioning in Patients Undergoing Hepatectomy
China135 participantsStarted 2023-11-02
Plain-language summary
Our primary aim is to investigate whether perioperative remote ischemic conditioning (PRIC) as an adjunctive treatment can improve postoperative recovery in patients undergoing hepatectomy as an adjunct to standard treatment.
Who can participate
Age range25 Years – 75 Years
SexALL
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Inclusion Criteria:
* Patients undergoing hepatectomy under general anesthesia
* American Society of Anesthesiology (ASA) grade of II \~ III
* Male and female patients, age 25 to 75 years
* New York Heart Association (NYHA) grade of I \~ III
Exclusion Criteria:
* Patients with limb deformity or peripheral vascular disease affecting upper limb function
* Patients with a medical history of nervous system, immune system and mental illness
* Patients who have received hepatectomy in the past, have important organ diseases or have undergone surgical treatment recently
* Patients who have recently used anti-inflammatory analgesics, anticoagulants, hormone drugs, immunosuppressants, and ATP-sensitive K-channel blockers (KATP)
* Preoperative severe renal insufficiency (serum creatinine \> 442 umol/L, with or without serum potassium \> 6.5 mmol/L, or the clinician-recognized need for renal replacement therapy), liver insufficiency (Child-Pugh grade C)
* Patients and/or their family members refuse to participate in the program
What they're measuring
1
Alanine aminotransferase (ALT)
Timeframe: 7 days
Trial details
NCT IDNCT06130436
SponsorThe Second Affiliated Hospital of Chongqing Medical University