This randomized clinical trial and laboratory study was conducted to: Compare the effectiveness of zinc-carbonated nano-hydroxyapatite, arginine, and fluoride-containing toothpastes for treating white spot lesions associated with orthodontically treated teeth by using: * Computerized image software analysis. * Energy dispersive X-ray analysis.
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the size
Timeframe: 1) Baseline 2) 3-month evaluation 3) 6-month evaluation
the color change
Timeframe: 1) Baseline 2) 3-month evaluation 3) 6-month evaluation