Organ Protective Effect of Cetirizine In Patients With Severe Burns (NCT06126991) | Clinical Trial Compass
UnknownPhase 1/2
Organ Protective Effect of Cetirizine In Patients With Severe Burns
China32 participantsStarted 2024-01-23
Plain-language summary
This prospective clinical trial aims to investigate the organ protective effects of cetirizine in patients with severe burns.
Who can participate
Age range12 Years – 90 Years
SexALL
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Inclusion Criteria:
* Signed and dated informed consent form
* Commitment to comply with the procedures and cooperation during the course
* TBSA \>30% and admitted within the first day after burns
* No severe compound injuries
Exclusion Criteria:
* History of allergy to drugs in the trial
* Postoperative complications that would interfere with the observation
* Mental illness and severe heart disease, hypertension
* Serious genetic diseases
* Incomplete clinical information (unclear diagnosis, incomplete medical history, incomplete medication records, etc.)
* Pregnancy/lactation
* Malignant tumors
* Organ insufficiency due to previous chronic diseases such as hypertension, diabetes mellitus or non-burning factors
* Serious adverse reactions
* Self-requested withdrawal