Guided Episodic Future Thinking to Increase Physical Activity Adherence and Promote Healthy Brain… (NCT06123182) | Clinical Trial Compass
RecruitingNot Applicable
Guided Episodic Future Thinking to Increase Physical Activity Adherence and Promote Healthy Brain Aging
United States160 participantsStarted 2024-02-23
Plain-language summary
The goal of this behavioral clinical trial is to learn how to increase physical activity in mid-life adults. Specifically, can guided imagery that includes creating mental pictures increase excitement about working out.
Participants will be asked to complete testing at the beginning of the study, following 6-weeks of an in-person exercise program, and 6-weeks after finishing the exercise program. Testing will include an exercise test, MRI, questionnaires, computer tasks, and a blood draw.
Who can participate
Age range45 Years – 65 Years
SexALL
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Inclusion Criteria:
* speak English
* have access to reliable communication (a telephone or cell phone, computer, etc.)
* normal or corrected to normal vision and hearing
* ambulatory (without the use of assistive devices)
* physically underactive
* able to give informed consent
* able to exercise continuously on the recumbent stepper exercise device for 4 minutes greater than or equal to 25 watts to demonstrate ability to perform exercise on stepper \& no aerobic exercise contraindications or other safety/physical concerns
* able to communicate with investigators, follow 2-step command \& correctly answer consent comprehension questions
* stable blood pressure and statin medication doses for 30 days as these affect vascular health/hemodynamics
* willing and able to safely enter magnetic resonance (MR) scanner and attempt the MR scan
* willing and able to attempt a blood draw
Exclusion Criteria:
* patients with arrhythmias or acute cardiac events will be excluded due to potential complications with the supervised moderate exercise
* at risk for hazard due to magnetic fields due to MR safety concerns
* have any neurologic or psychiatric disorder except depression, anxiety (including post-traumatic stress disorder)
* have history of seizures or head trauma due to MR data quality