Guided Episodic Future Thinking to Increase Physical Activity Adherence and Promote Healthy Brain… (NCT06123182) | Clinical Trial Compass
RecruitingNot Applicable
Guided Episodic Future Thinking to Increase Physical Activity Adherence and Promote Healthy Brain Aging
United States160 participantsStarted 2024-02-23
Plain-language summary
The goal of this behavioral clinical trial is to learn how to increase physical activity in mid-life adults. Specifically, can guided imagery that includes creating mental pictures increase excitement about working out.
Participants will be asked to complete testing at the beginning of the study, following 6-weeks of an in-person exercise program, and 6-weeks after finishing the exercise program. Testing will include an exercise test, MRI, questionnaires, computer tasks, and a blood draw.
Who can participate
Age range
45 Years – 65 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* speak English
* have access to reliable communication (a telephone or cell phone, computer, etc.)
* normal or corrected to normal vision and hearing
* ambulatory (without the use of assistive devices)
* physically underactive
* able to give informed consent
* able to exercise continuously on the recumbent stepper exercise device for 4 minutes greater than or equal to 25 watts to demonstrate ability to perform exercise on stepper \& no aerobic exercise contraindications or other safety/physical concerns
* able to communicate with investigators, follow 2-step command \& correctly answer consent comprehension questions
* stable blood pressure and statin medication doses for 30 days as these affect vascular health/hemodynamics
* willing and able to safely enter magnetic resonance (MR) scanner and attempt the MR scan
* willing and able to attempt a blood draw
Exclusion Criteria:
* patients with arrhythmias or acute cardiac events will be excluded due to potential complications with the supervised moderate exercise
* at risk for hazard due to magnetic fields due to MR safety concerns
* have any neurologic or psychiatric disorder except depression, anxiety (including post-traumatic stress disorder)
* have history of seizures or head trauma due to MR data quality
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.