The Effect Of Resuscitation Guided By Two Different Dynamic Parameters On Time To Normalization Of The Capillary Refill Time In Adult Patients With Septic Shock

Inclusion Criteria: * adult patients ( ≥ 18 years) of either gender with septic shock according to the Sepsis-3 Exclusion Criteria: * Known history of any cardiac pathology, acute coronary syndrome, cardiac dysrhythmias (as a primary diagnosis), acute pulmonary edema or known poor systolic cardiac function (left ventricular ejection fraction \< 50%). * Body mass index ≥ 35 kg/m2 . * Concomitant acute respiratory distress syndrome) or high PEEP (\> 10 cmH2O) requirements on mechanical ventilation (MV). * Child B or C liver cirrhosis. * End-stage renal disease with or without dialysis. * Pregnancy. * Multi-organ system failure. * Active hemorrhage. * Head trauma. * Intra-abdominal hypertension (\> 15 mmHg). * Declined to consent.