TerminatedNot Applicable

Changes in Host Gene Expression to Differentiate Between Systemic Inflammation and Infection After Major Surgery

Stopped: Funding stopped

Netherlands61 participantsStarted 2024-12-01

Plain-language summary

Changes in host gene expression may provide additional information to diagnose postoperative infection and improve outcome after surgery. This study aims to validate the early diagnostic performance of specific gene signatures for differentiating infection from non-infected SIRS or uncomplicated postoperative course in blood sampes of adult patients undergoing major noncardiac surgery.

Who can participate

Age range18 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Age \>18 years * Major noncardiac surgery with infection risk \>20% Exclusion Criteria: * Age \<18 years * Emergency surgery * Inability to provide informed consent.

What they're measuring

Postoperative infection

Timeframe: 30 days

Trial details

NCT IDNCT06116656

SponsorSt. Antonius Hospital

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2025-03-01

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