UnknownPhase 4

Effect of Vachellia Nilotica Versus Sodium Hypochlorite as Root Canal Irrigant on Postoperative Pain and Bacterial Load Reduction in Mandibular Premolar Teeth With Necrotic Pulp

46 participantsStarted 2023-11

Plain-language summary

The aim of this study is to assess the effect of V. nilotica extract solution versus 2.5% NaOCl on the intensity of postoperative pain and the amount of bacterial load reduction.

Who can participate

Age range20 Years – 40 Years

SexALL

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Inclusion criteria

✓. Systemically healthy patient (ASA I, II).
✓. Age between 20 and 40 years.
✓. Male or female.
✓. Patient who is able to sign and comprehend the pain scale (committed patient).
✓. Mandibular single rooted premolars having the following criteria:

Exclusion criteria

✕. Medically compromised patients (ASA III or IV).
✕. Teeth with:
✕. Patients who could not interpret the NRS.
✕. Patients with diabetes, immune-compromising, and immunosuppression disease and pregnant women will be also excluded.
✕. History of intolerance to NSAIDs.

What they're measuring

post operative pain.

Timeframe: At 6, 12, 24, and 48 hours postoperatively (post instrumentation and post obturation)

Trial details

NCT IDNCT06116214

SponsorCairo University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2024-02

Contact for this trial

Gozlan FS Mohamed

+201033766933 gozlan.fouad@dentistry.cu.edu.eg

View on ClinicalTrials.gov More Necrotic Pulp trials