CompletedPhase 2

Outcome of Moderate Severity in OPC Poisoning Patients When Treated With Pralidoxime

Bangladesh96 participantsStarted 2022-06-01

Plain-language summary

This open level randomized controlled trial will be conducted in the department of medicine at Sir Salimullah Medical College and Mitford Hospital. Clinical severity will be assessed by the POP (Peradeniya Organophosphorus Poisoning) scale of admitted patients having a history of organophosphorus poisoning within 24 hours with clinical features and physical evidence of poisoning consumed. Only moderate severity (POP Scale score 4-7) of OPC (Organophosphorus compound) patients will be included in this study. Then one group of patients will be treated with atropine and pralidoxime and another group will be treated with atropine. The outcome will be noted as clinical improvement or recovery. hospital stay, requirement of ICU, death.

Who can participate

Age range12 Years

SexALL

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Inclusion criteria

✓. Patient having history of organophosphorus poisoning within 24 hours with features of moderate severity. (POP scale score 4-7)
✓. Age above 12 years

Exclusion criteria

✕. Mixed poisons along with organophosphorus compound,
✕. Patients with known case chronic diseases such as chronic lung disease, chronic kidney disease, Heart failure, malignancy, chronic liver disease

What they're measuring

Mortality rate

Timeframe: 1 year

Trial details

NCT IDNCT06111352

SponsorSir Salimullah Medical College Mitford Hospital

Sponsor typeOTHER_GOV

Study typeINTERVENTIONAL

Primary completion2023-09-30

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