CompletedNot Applicable

Cannabidiol Effects on Blood Alcohol Level and Intoxication

United States37 participantsStarted 2021-03-09

Plain-language summary

The main objectives of this study were to test if 2 different doses of Cannabidiol (compared to placebo) alter 1) breath alcohol concentration, 2) craving and subjective responses to alcohol or 3) cognitive performance following a standard dose of alcohol.

Who can participate

Age range

21 Years – 60 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * 21-60 years old * able to provide consent * willing to consume CBD during the study * report heavy drinking (\>5 drinks \[\>4 for women\] per occasion on at least 5 days/month in the past 3 months) * not cannabis/CBD naive (i.e. THC or CBD use at least once in the past year), do not use cannabis regularly (i.e., less than monthly over past year), and no past-month cannabis use. Exclusion Criteria: * a regular or recent cannabis user (i.e. they used cannabis more often than monthly during the past year or used cannabis in the past month) * were seeking treatment a substance use disorder (SUD) including AUD, taking medications to treat bipolar or psychotic disorders * using nicotine every day * taking blood thinning medications * reported having a major medical condition contraindicating alcohol or CBD use (e.g., liver disease or heart disease) * reported current suicidality * met criteria for psychotic disorder, bipolar disorder or a current major depressive episode, * reported using illicit drugs in the 30 days prior to beginning the study or tested positive for any illicit drugs * were pregnant, breastfeeding or trying to become pregnant.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Breath Alcohol Concentration (BrAC)

Timeframe: Timepoint 1 (20 minutes after alcohol consumption is complete)

Breath Alcohol Concentration (BrAC)

Timeframe: Timepoint 2 (30 minutes after Timepoint 1)

Breath Alcohol Concentration (BrAC)

Timeframe: Timepoint 3 (30 minutes after Timepoint 2)

Breath Alcohol Concentration (BrAC)

Timeframe: Timepoint 4 (30 minutes after Timepoint 3)

Breath Alcohol Concentration (BrAC)

Timeframe: Timepoint 5 (30 minutes after Timepoint 4)

Breath Alcohol Concentration (BrAC)

Timeframe: Timepoint 6 (30 minutes after Timepoint 6)

Breath Alcohol Concentration (BrAC)

Timeframe: Timepoint 7 (30 minutes after Timepoint 6)

Trial details

NCT IDNCT06105138

SponsorColorado State University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2022-03-03

Results submitted2023-11-29

View on ClinicalTrials.gov More Alcohol Use Disorder trials

Who can participate

Age range

21 Years – 60 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

Breath Alcohol Concentration (BrAC)

Timeframe: Timepoint 1 (20 minutes after alcohol consumption is complete)

Breath Alcohol Concentration (BrAC)

Timeframe: Timepoint 2 (30 minutes after Timepoint 1)

Breath Alcohol Concentration (BrAC)

Timeframe: Timepoint 3 (30 minutes after Timepoint 2)

Breath Alcohol Concentration (BrAC)

Timeframe: Timepoint 4 (30 minutes after Timepoint 3)

Breath Alcohol Concentration (BrAC)

Timeframe: Timepoint 5 (30 minutes after Timepoint 4)

Breath Alcohol Concentration (BrAC)

Timeframe: Timepoint 6 (30 minutes after Timepoint 6)

Breath Alcohol Concentration (BrAC)

Timeframe: Timepoint 7 (30 minutes after Timepoint 6)