CompletedNot Applicable

Cannabidiol Effects on Blood Alcohol Level and Intoxication

United States37 participantsStarted 2021-03-09

Plain-language summary

The main objectives of this study were to test if 2 different doses of Cannabidiol (compared to placebo) alter 1) breath alcohol concentration, 2) craving and subjective responses to alcohol or 3) cognitive performance following a standard dose of alcohol.

Who can participate

Age range21 Years – 60 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * 21-60 years old * able to provide consent * willing to consume CBD during the study * report heavy drinking (\>5 drinks \[\>4 for women\] per occasion on at least 5 days/month in the past 3 months) * not cannabis/CBD naive (i.e. THC or CBD use at least once in the past year), do not use cannabis regularly (i.e., less than monthly over past year), and no past-month cannabis use. Exclusion Criteria: * a regular or recent cannabis user (i.e. they used cannabis more often than monthly during the past year or used cannabis in the past month) * were seeking treatment a substance use disorder (SUD) including AUD, taking medications to treat bipolar or psychotic disorders * using nicotine every day * taking blood thinning medications * reported having a major medical condition contraindicating alcohol or CBD use (e.g., liver disease or heart disease) * reported current suicidality * met criteria for psychotic disorder, bipolar disorder or a current major depressive episode, * reported using illicit drugs in the 30 days prior to beginning the study or tested positive for any illicit drugs * were pregnant, breastfeeding or trying to become pregnant.

What they're measuring

Breath Alcohol Concentration (BrAC)

Timeframe: Timepoint 1 (20 minutes after alcohol consumption is complete)

Breath Alcohol Concentration (BrAC)

Timeframe: Timepoint 2 (30 minutes after Timepoint 1)

Breath Alcohol Concentration (BrAC)

Timeframe: Timepoint 3 (30 minutes after Timepoint 2)

Breath Alcohol Concentration (BrAC)

Timeframe: Timepoint 4 (30 minutes after Timepoint 3)

Breath Alcohol Concentration (BrAC)

Timeframe: Timepoint 5 (30 minutes after Timepoint 4)

Breath Alcohol Concentration (BrAC)

Timeframe: Timepoint 6 (30 minutes after Timepoint 6)

Breath Alcohol Concentration (BrAC)

Timeframe: Timepoint 7 (30 minutes after Timepoint 6)

Breath Alcohol Concentration (BrAC)

Timeframe: Timepoint 8 (30 minutes after Timepoint 9)

Trial details

NCT IDNCT06105138

SponsorColorado State University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2022-03-03

Results submitted2023-11-29

View on ClinicalTrials.gov More Alcohol Use Disorder trials

Who can participate

Age range21 Years – 60 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

Breath Alcohol Concentration (BrAC)

Timeframe: Timepoint 1 (20 minutes after alcohol consumption is complete)

Breath Alcohol Concentration (BrAC)

Timeframe: Timepoint 2 (30 minutes after Timepoint 1)

Breath Alcohol Concentration (BrAC)

Timeframe: Timepoint 3 (30 minutes after Timepoint 2)

Breath Alcohol Concentration (BrAC)

Timeframe: Timepoint 4 (30 minutes after Timepoint 3)

Breath Alcohol Concentration (BrAC)

Timeframe: Timepoint 5 (30 minutes after Timepoint 4)

Breath Alcohol Concentration (BrAC)

Timeframe: Timepoint 6 (30 minutes after Timepoint 6)

Breath Alcohol Concentration (BrAC)

Timeframe: Timepoint 7 (30 minutes after Timepoint 6)

Breath Alcohol Concentration (BrAC)

Timeframe: Timepoint 8 (30 minutes after Timepoint 9)