RecruitingNot Applicable

The Correlation Between Ovarian Function and Serum Biomarkers

China35 participantsStarted 2023-10-25

Plain-language summary

The goal of this observational study is to find differences in serum biomarkers between ovarian function and normal individuals.

Who can participate

Age range18 Years – 45 Years

SexFEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

✓. The selection criteria for healthy individuals are follows.
✓. The selection criteria for DOR patients are follows.
✓. Selection criteria for POI patients are follows.

Exclusion criteria

✕. Patients with congenital gonadal developmental abnormalities or a family history similar to "early menopause".
✕. Patients with acquired organic lesions or decreased ovarian function caused by ovarian surgery.
✕. Patients who have undergone artificial cycle therapy with Western medicine or other endocrine treatments within the past three months.
✕. Patients with severe primary diseases and mental disorders such as crdiovascular, cerebrovascular, liver, kidney, and hematopoietic system.
✕. Patients during lactation or pregnancy.
✕. Patients who are allergic to the drugs used in this study or have a history of allergic reactions to traditional Chinese medicine.

What they're measuring

copper

Timeframe: On the 2~4th day of menstruation (amenorrhea patients on the enrolled week)

Iron ion

Timeframe: On the 2~4th day of menstruation (amenorrhea patients on the enrolled week)

ceruloplasmin, CP

Timeframe: On the 2~4th day of menstruation (amenorrhea patientson the enrolled week)

CuZn-Superoxide Dismutase, CuZn-SOD/SOD1

Timeframe: On the 2~4th day of menstruation (amenorrhea patients on the enrolled week)

Malondialdehyde，MDA

Timeframe: On the 2~4th day of menstruation (amenorrhea patients on the enrolled week)

Trial details

NCT IDNCT06096766

SponsorShi Yun

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2025-11-11

Contact for this trial

Yun Shi, PhD

13717926522 zysyun@163.com

View on ClinicalTrials.gov More Premature Ovarian Insufficiency trials

Who can participate

Age range18 Years – 45 Years

SexFEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

✓. The selection criteria for healthy individuals are follows.
✓. The selection criteria for DOR patients are follows.
✓. Selection criteria for POI patients are follows.

Exclusion criteria

✕. Patients with congenital gonadal developmental abnormalities or a family history similar to "early menopause".
✕. Patients with acquired organic lesions or decreased ovarian function caused by ovarian surgery.
✕. Patients who have undergone artificial cycle therapy with Western medicine or other endocrine treatments within the past three months.
✕. Patients with severe primary diseases and mental disorders such as crdiovascular, cerebrovascular, liver, kidney, and hematopoietic system.
✕. Patients during lactation or pregnancy.
✕. Patients who are allergic to the drugs used in this study or have a history of allergic reactions to traditional Chinese medicine.

What they're measuring

copper

Timeframe: On the 2~4th day of menstruation (amenorrhea patients on the enrolled week)

Iron ion

Timeframe: On the 2~4th day of menstruation (amenorrhea patients on the enrolled week)

ceruloplasmin, CP

Timeframe: On the 2~4th day of menstruation (amenorrhea patientson the enrolled week)

CuZn-Superoxide Dismutase, CuZn-SOD/SOD1

Timeframe: On the 2~4th day of menstruation (amenorrhea patients on the enrolled week)

Malondialdehyde，MDA

Timeframe: On the 2~4th day of menstruation (amenorrhea patients on the enrolled week)