RecruitingNot Applicable

tACS to Enhance Language Abilities

United States120 participantsStarted 2024-07-12

Plain-language summary

The goal of this study is to see if transcranial alternating current stimulation (tACS) can be used to enhance language abilities in people with post-stroke aphasia. Participants will receive real and sham tACS in conjunction with various language tests. Researchers will compare the post-stroke aphasia group with aged matched controls to see if brain response to tACS differs between groups.

Who can participate

Age range18 Years – 85 Years

SexALL

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Inclusion criteria

✓. Presence of aphasia
✓. Suffered a single, left hemisphere stroke
✓. Stroke ≥6 months old (chronic) at the time of enrollment
✓. Right-handedness
✓. Must be able to understand the nature of the study, and give informed consent

Exclusion criteria

✕. Inability to understand the nature of the study
✕. Marked naming impairment
✕. Impaired non-verbal, conceptual processing
✕. History of significant medical or neurological disorder (other than stroke)
✕. History of significant or poorly controlled psychiatric disorders
✕. Current abuse of alcohol or drugs, prescription or otherwise
✕. Nursing a child, pregnancy, or intent to become pregnant during the study
✕. Clinically significant hearing loss

What they're measuring

Performance on the Blocked-Cyclic Naming (BCN) Task

Timeframe: 5-10 minutes after a single session of active (alpha tACS) and sham (fake tACS).

Trial details

NCT IDNCT06092814

SponsorUniversity of Pennsylvania

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2028-08-31

Contact for this trial

Daniela Sacchetti, MS

215 573 4336 danielas@pennmedicine.upenn.edu

View on ClinicalTrials.gov More Stroke trials